Triterpenos e cromonas isolados das folhas de Licania arianeae (Chrysobalanaceae)

Abstract

Solvent partition and chromatographic fractionation of the hexane and methanolic extracts from the leaves of Licania arianeae afforded the pentacyclic triterpenes 3ahydroxy-urs-12-en-28-oic acid, 3a-24-dihydroxy-olean-12en-28-oic acid, 3a,19a-24 trihydroyi-urs- 12-en-28-oic acid, 3b-hydroxy-olean-12-en-28-oic acid and 3b-hydroxy-urs- 12-en-28-oic acid, the saponins 3b-O-b-D-glucopyranosyl-24-hydroxy-urs-12-en-28-oic acid and 3b-O-b-D-glucopyranosyl-19a,24-dihydroxy-urs-12-en-28-oic acid, and the chromones 5,7-diidroxi-2-dotricontyl-chromone,. 5,7-diidroxi-2-untricontyl-chromone, 5,7- diidroxi-2-tricontyl-chromone, 5,7-diidroxi-2-noneicosyl-chromone, 5,7-diidroxi-6-cloro-2- dotricontyl-chromone, 5,7-diidroxi-6-cloro-2-untricontyl-chromone, 5,7-diidroxi-6-cloro-2- tricontyl-chromone, 5,7-diidroxi-6-cloro-2-noneicosyl-chromone. The structures were defined by 1R and 1H and 13C-NMR (ID and 2D) spectral analysis of the natural substances and acetyl and methyl derivatives along with comparison with literature data. The FAB-MS spectral analysis of the chromone methyl ethers were used to define the structures of the natural chromones. The 3a-hydroxytriterpenes acids, saponins and chromones have been isolated for the first time from the Licania genus.