1. TEDE
  2. CAMPUS SEROPÉDICA
  3. Programa de Pós-Graduação em Biologia Animal
  4. Doutorado em Biologia Animal
???item.export.label??? ???item.export.type.endnote??? ???item.export.type.bibtex???

Please use this identifier to cite or link to this item: https://tede.ufrrj.br/jspui/handle/jspui/5595
Full metadata record
DC FieldValueLanguage
dc.creatorPolo, Patrícia de Almeida-
dc.creator.Latteshttp://lattes.cnpq.br/6888429121952012por
dc.contributor.advisor1Reis, Luis Carlos-
dc.contributor.referee1Silva, Hélio Ricardo da-
dc.contributor.referee2Piratelli, Augusto João-
dc.contributor.referee3Ferreira, Ildemar-
dc.contributor.referee4Mendes, Lys Angela Favaroni-
dc.contributor.referee5Luis Carlos Reis-
dc.date.accessioned2022-05-02T18:33:09Z-
dc.date.issued2009-03-06-
dc.identifier.citationPOLO, Patrícia de Almeida. Estudo neurobiológico de componentes do sono em codornas (Coturnix japonica) (Temminck Schlegel, 1849) (Aves: Galliformes). 2009. 78 f. Tese (Doutorado em Biologia Animal) - Instituto de Ciências Biológicas e da Saúde, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ, 2009.por
dc.identifier.urihttps://tede.ufrrj.br/jspui/handle/jspui/5595-
dc.description.resumoEsse trabalho deu continuidade a um achado incidental do Laboratório de Fisiologia Animal da UFRRJ, no Departamento de Ciências Fisiológicas, no qual, codornas tratadas perifericamente com serotonina, em um estudo sobre comportamento alimentar, apresentaram comportamentos semelhantes ao sono. A partir dessa evidência, a idéia de que a serotonina permeia a barreira hematoencefálica de aves, diferentemente de mamíferos, incitou novas investigações neurofarmacológicas e comportamentais. Foi realizado, primeiramente, um estudo com antagonistas e agonistas de receptores serotoninérgicos, confirmando a permeabilidade da barreira hematoencefálica de codornas à essa amina biogênica e sua participação em mecanismos centrais envolvidos na regulação de comportamentos semelhantes aos do sono. Esse trabalho resultou em uma publicação na Brazilian Joumal of Biology, em 2007, intitulada "Behavioral and neuropharmacological evidence that serotonin crosses the blood-brain barrier in Coturnix japonica (Gallifonnes: Aves)". Levando-se em consideração que a serotonina é precursora da melatonina, e que esta última está envolvida no controle do ritmo circadiano, continuou-se a investigação, em tomo das alterações séricas de melatonina, mediante administração do precursor da serotonina, L-5-hidróxi-triptofano. Esse estudo resultou na publicação do segundo artigo na Brazilian Journal of Biology, em 2007, "Nocturnal plasma leveis of melatonin in quails (Coturnix japonica) injected with L-5-hydroxy-tryptophan". Uma vez que os comportamentos relacionados ao sono envolvem uma série de inibições centrais e que o ácido y-amino-butírico (GABA) é o maior neurotransmissor central do sistema nervoso central, continuou-se a explorar neurofarmacológica e comportamentalmente, o sono em codornas, abordando-se um tipo de receptor gabaérgico, o complexo receptor GABAA. O estudo resultou na última publicação desse doutoramento, Study of GABAA receptors on the sleep-lik:e behavior in Coturnix japonica (Temminck Schlegel, 1849) (Galliformes: Aves), na Joumal of Comparative Physiology A, em 2008. O objetivo dessa tese não foi traçar um paralelo filogenético entre aves e mamíferos, entretanto, muitas evidências foram inevitáveis. Certamente, esse trabalho contribuiu para ampliar o conhecimento científico sobre os elementos estudados. Ainda há muito o que se investigar a respeito do sono, não só em aves, como também em mamíferos.por
dc.description.abstractThis work gives continuity to an incidental discovery from the Laboratory of Animal Plhysiology of UFRRJ, in the Department of Physiologic Science in which quails were treated periphericaly by serotonin, in a study of feeding behavior became sleep. From this evidence, the idea of which serotonin permeates the blood-brain barrier (BBB) of the birds, differently to mammals, incited new investigations about neuropharmacology and regarding this issue. Firstly, a study of antagonists e agonists of serotonergic receptors was held, confirming the permeability of the barrier of (BBB) of quails to serotonin and your participation in the central mechanisms involved in the regulation of the similar sleep-like behaviors. This research resulted in a publication of a first in the Brazilian Journal of Biology, in 2007, entitled "Behavioral and neuropharmacological evidence that serotonin crosses the bloodbrain barrier in Cortunix japonica (Galliformes: Aves). Taking into consideration that the serotonin is the precursor of melatonin and this last one is involved in the control of the circadian rhythm, we continued with the investigation about the plasma leveis of melatonin, by means of application of the serotonin precursor, L-5-hydroxy-tryptophan. This study resulted in the publication of a second article in the Brazilian Journal of Biology, in 2007, "Nocturnal plasma levels of melatonin in quails (Cortunix japonica) injected with L-5-hydroxy-tryptophan". Once the behaviors related to sleep involves a series of central inhibition and the y-aminobutyric acid (GABA) is the biggest central inhibitory neurotransmitter of the central nervous system, we continued exploring behavioral and neuropharmacologically broaching the one type of gabaergic receptor, aiming the sleep of quails, the complex receptor GABAA. This work resulted in the third and last publication of this doctorate work, "Study of GABAA receptors on the sleep-like behavior in Cortunix japonica (Temminck Schlegel, 1849) (Galliformes: Aves)", in the Journal of Comparative Physiology A, in 2008. Toe aim of this thesis was not to draw a parallel between birds and mammals. However, many evidences were inevitable. Certainly, this research contributed to increase the scientific knowledge of the analysed elements. There is still too much to investigate concerning sleep, not only in birds, but also in mammals.eng
dc.description.provenanceSubmitted by Jorge Silva (jorgelmsilva@ufrrj.br) on 2022-05-02T18:33:09Z No. of bitstreams: 1 2009 - Patricia de Almeida Polo.pdf: 1032409 bytes, checksum: 53b4b0668b4466242679b8e4b98eefb7 (MD5)eng
dc.description.provenanceMade available in DSpace on 2022-05-02T18:33:09Z (GMT). No. of bitstreams: 1 2009 - Patricia de Almeida Polo.pdf: 1032409 bytes, checksum: 53b4b0668b4466242679b8e4b98eefb7 (MD5) Previous issue date: 2009-03-06eng
dc.formatapplication/pdf*
dc.thumbnail.urlhttps://tede.ufrrj.br/retrieve/69064/2009%20-%20Patricia%20de%20Almeida%20Polo.pdf.jpg*
dc.languageporpor
dc.publisherUniversidade Federal Rural do Rio de Janeiropor
dc.publisher.departmentInstituto de Ciências Biológicas e da Saúdepor
dc.publisher.countryBrasilpor
dc.publisher.initialsUFRRJpor
dc.publisher.programPrograma de Pós-Graduação em Biologia Animalpor
dc.relation.referencesADACHI, N.; TOMONAGA, N.; TACHIBANA, T.; DENBOW, D.M.; FURUSE, M. Epigallocatechin gallate attenuates acute stress responses through GABAergic system in the brain. Eur J Pharmacol v. 631, p.171–175, 2006. ADELL, A.; ARTIGAS, F. Regulation of the Release of 5-hydroxytryptamine in the Median raphe nucleus of the rat by Catecholaminergic Afferents. European Journal of Neuroscience. v. 11, p. 2305-2311, 1999. ALI, M.; JHA, S.K.; KAUR, S.; MALLICK, B.N. Role of GABA: a receptor in the preoptic area in the regulation of sleepwakefulness and rapid eye movement sleep. Neurosci Res v. 33, p. 245–250. 1999. ARGIOLAS, A.; MELIS, M.R.. The neuropharmacology of yawning. Eur. J. Pharmacol., v. 343, p. 1-16, 1998. ARGIOLAS, A.; MELIS, M.R.; MURGIA, S.; SCHIÖTH, H.B. ACTHand α-MSH-induced grooming, stretching, yawning and penile erection in male rats: site of action in the brain and role of melanocortin receptors. Brain Research Bulletin. v. 51, n. 5, p. 425-431, 2000. ARNAUD, C.; GAUTHIER, P.; GOTTESMANN, C.. Study of a GABAC receptor antagonist on sleep-waking behavior in rats. Psychopharmacology, v. 154, p. 415-419, 2001. AYALA-GUERRERO, F.; MEXICANO, G.; RAMOS, J.J. Sleep characteristics in the turkey Meleagris gallopavo. Physiol. Behav., v. 78, p. 435-440, 2003. AZMITIA, E. C. The CNS serotonergic system: progression toward a collaborative organization, p. 61-73. In: MELTZER, H. Y. (ed), Psychopharmacology: Third Generation of Progress, New York: Raven Press, 1987. BABA, T.; BLACK, K.L.; IBEZAKI, K.; CHEN, K.; BECKER, D.P.. Intracarotid Infusion of Leukotriene C4 selectively increases blood-brain barrier permeability after focal ischemia in rats. Journal of Cerebral Blood Flow and Metabolism. v. 11, p. 638-643, 1991. BADAUÊ-PASSOS JR., D.; VENTURA, R.R.; SILVA, L.F.S.; OLIVARES, E.L.;REIS, L.C. Effect of brain serotoninergic stimulation on sodium appetite in euthyroid and hypothyroid rats. Exp. Physiol., v. 88, p. 251-260, 2003. BAYLÉ, J.D.; RAMADE, F.; OLIVER, J. Stereotaxic topography of the brain of the quail (Coturnix coturnix japonica). J. Physiol. v. 68, p. 219-241, 1974. BEALE, M.D.; MURPHREE, T.M. Excessive yawning and SSRI therapy. Int. J. Neuropsychopharmacol., v. 3, p. 275-276, 2000. BENDOTTI, C.; SAMANIN, R. The Role of Putative 5-HT1A and 5-HT1B receptors in the control of feeding in rats. Life Science, v. 41, n. 5, p. 635-642, 1987. BENTLEY, G.E. Unraveling the enigma: the role of melatonin in seasonal process in birds. Microsc. Res. Tech., v. 53, n. 1, p. 63-71, 2001. BERNARD, E.A.; SKOLNICK, P.; OLSEN, R.W.; MOHLER, H.; SIEGHART, W.; BIGGIO, G.; BRAESTRUP, C.; BATESON, A.N.; LANGER, S.Z. International Union of Pharmacology. XV. Subtypes of γ-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function. Pharmacological Reviews. v. 50, n. 2, p. 291-313, 1998. BLACK, KL. Biochemical opening of the blood-brain barrier. Adv. Drug Deliv. Rev., v. 15, p. 37-52, 1995. BLUNDEL, J.E. Serotonin and appetite. Neuropharmacology. v. 23, n. 12B, p. 1537-1551, 1984. BOADLE-BIBER, MC. Regulation of serotonin synthesis. Prog. Biophys. Molec. Biol., v. 60, p. 1-15, 1993. BOBBO, D.; GALVANI, F.; MASCETTI, G.G.; VALLORTIGARA, G. Light exposure of the chick embryo influences monocular sleep. Behavioural Brain Research. v. 134, p. 447-466, 2002. BOGDANSKI, D.F.; BONOMI, L.; BRODIE, B.B. Occurrence of serotonin and catecholamines in brain and peripheral organs of various vertebrate classes. Life Sciences. n. 1, p. 80-84, 1963. BORMANN, J. The ‘ABC’ of GABA receptors. Trends Pharmacol Sci, v. 21, p.:16–19, 2000. BRIGHTMAN, M. W. Morphology of blood-brain interfaces. Exp. Eye Res., v. 76, p. 87-96, 1977. BUBNOFF, N., HEIDENHAIN, R., Ueber Erregungs-hemmungsvorgänge innerhalb der motorischen hirncentren. In: Pflüger, E.F.W. (Ed.), Arch. Gesam. Physiol. Bonn: Emil Strauss Verlag, 1881, p. 137-202. BRUN, S.R.M.; LUZ, V.; FERNANDEZ, M.; PASCHOALINI, M.A.; MARINO-NETO, J. Atypical angiotensin receptors may mediate water intake induced by central injections of angiotensin II and of serotonin in pigeons. Regulatory Peptides. v. 98, p. 127-135, 2001. CAMPBELL, S.S.; TOBLER, I. Animal sleep: a review of sleep duration across phylogeny. Neurosci Biobehav Rev, v. 8, p.269–300, 1984. CAVALLO, A.; RICHARDS, G.E.; MEYER, W.J.; WALDROP, R.D. Evaluation of 5-hydroxytryptophan administration as a test of pineal function in humans. Horm. Res., v. 27, p. 69-73, 1987. CESPUGLIO, R.; HOUDOUIN, F.; OULERICH, M.; EL MANSARI, M.; JOUVET, M. Axonal and somato-dendritic modalities of serotonin release: their involvement in Sleep Preparation, Triggering and Maintenance. J Sleep Res. vol. 1, n. 3, p. 150-156, 1992. CHALLET, E.; MICELI, D.; PIERRE, J.; REPÉRANT, J. Distribution of serotoninimmunoreactivity in the brain of the Pigeon (Columba livia). Anat Embriol. v. 193, p. 209-227, 1996. CHAMAS, F.; SEROVA, L.; SABBAN, E.L. Tryptophan hydroxylase mRNA levels are elevated by repeated immobilization stress in rat raphe nuclei but not in pineal gland. Neuroscience Letters., v. 267, p. 157-160, 1999. CHIKAZAWA, H.; FUJIOKA, T.; WATANABE, T. Catecholamine-containing neurons in the mesencephalic tegmentum of the chicken. Light, fluorescence and electron microscopic studies. Anatomy and Embryology,. v. 164, p. 303-313, 1982. CHIKAZAWA, H.; FUJIOKA, T.; WATANABE, T. Bulbar catecholaminergic neurons projecting to the thoracic spinal cord of the chicken. Evans blue labeling study in combination with catecholamine histofluorescence. Anatomy and Embryology, v. 167, p. 411-423, 1983. CHOU-GREEN, J.M.; HOLSCHER, T.D.; DALLMAN, M.F.; AKANA, S.F. Repeated stress in young and old 5-HT2C receptor knockout mice. Physiology & Behavior, v. 79, p. 217-226, 2003. CIRELLI, C.; TONONI, G. Is sleep essential? PLoS Biol., v.6, p.1605–1611, 2008. CLÉNET, F.; HASCOËT, M.; FILLION, G.; GALONS, H.; BOURIN, M. Role of GABA-ergic and serotonergic systems in the anxiolytic-like mechanism of action of a 5-HT-moduline antagonist in the mouse elevated plus maze. Behavioural Brain Research, v. 158, p. 339-348, 2005. COLOM, L.V.; SAGGAU, P. Spontaneous interictal-like activity originates in multiple areas of the CA2-CA3 region of hippocampal slices. J Neurophysiol., v 71, p.1574–1585, 1994. COOPER, J.R.; BLOOM, F.E.; ROTH, R.H. Serotonin (5-Hydroxytryptamine) and Histamine. In: BLOOM, F. E. et al. (Eds.). The Biochemical basis of neuropharmacology, 7th ed., New York: University Press, 1996. p. 352-409. CORREALE, P. The Occurrence and Distribution of 5-hydroxytryptamine (Enteramine) in the Central Nervous System of Vertebrates. Journal of Neurochemistry. v. 1, p. 22-31, 1956. COS, S.; FERNÁNDEZ, R.; GÜÉZMES, A.; SANCHES-BARCELÓ, E.J. Influence of melatonin on invasive and metastatic properties of MCF-7 human breast cancer cells. Cancer Research., v. 58, p. 4383-4390, 1988. COZZI, B.; VIGLIETTI-PANZICA, C.; ASTE, N.; PANZICA, G.C. The serotoninergic system in the brain of the Japanese quail. An immunohistochemical study. Cell Tissue Res., v. 263, p. 271-284, 1991. CREUTZFELDT, O.; BAUMGARTNER, G.; SCHOEN, L. Reaktionen einzelner neurons des senso-motorischen cortex nach elektrischen reizen. I hemmung und eregung nach direkten und contralateralen einzelreizen. Arch. Psychiat. Nervenkrankh., v. 194, p.597-619, 1956. CURZON, G. Serotonin and apetite: neuropharmacology of serotonin. Ann. N. Y. Acad. Sci., v. 600, p. 521-531, 1990. CURZON, G. Effects of Tryptophan and of 5-hydroxytryptamine receptor subtype agonists on feeding. Adv. Exp. Med. Biol., v. 294, p. 377-388, 1991. DAQUIN, G.; MICALLEF, J.; BLIN, O. Yawning. Sleep Med. Rev., v. 5, p. 299-312, 2001. DATTA, S.; SIWEK, A.D. Excitation of the brain stem pedunculopontine tegmentum cholinergic cells induces wakefulness and REM sleep. J. Neurophysiol., v. 77, p. 2975-2988, 1997. DEBOER, T.; SANFORD, L.D.; ROSS, R.J.; MORRISON, A.R. Effects of electrical stimulation in the amygdala on ponto-geniculo-occipital waves in rats. Brain Research, v. 793, p. 305-310, 1998. DENBOW, D.M. Induction of food intake by a GABAergic mechanism in the turkey. Physiol Behav., v. 49, p.485–488, 1991. DOGER, E.; UBBÁ-HOLMGREN, R.; EGUIBAR, J.R.; HOLMGREN, B. GABAergic modulation of yawning behavior. Pharmacology Biochemistry & Bahavior, v. 34, p. 237-240, 1989. DUBÉ, L.; PARENT, A. The Monoamine-containing neurons in avian brain I. A study of the brain stem of the chicken (Gallus domesticus) by means of fluorescence and acetylcholinesterase histochemistry. The Journal of Comparative Neurology., v. 196, p. 695-708, 1981. DUPORT, S.; ROBERT, F.; MULLER, D.; GRAU, G.; PARISI, L.; STOPPINI, L. An In Vitro blood-brain barriei model: cocultures between endothelial cells and organotypic brain slice cultures. Proc. Natl. Acad. Sci., v. 95, p. 1840-1845, 1998. EVANS, L.; GOLSHAN, S.; KELSOE, J.; RAPAPORT, M.; RESOVSKY, K.; SUTTON, L.; GILLIN, J.C. Effects of rapid tryptophan depletion on sleep electroencephalogram and mood in subjects with partially remitted depression on bupropion. Neuropsychopharmacology, v 27, n. 6, p. 1016-1026, 2002. EVARTS, E.V.; FLEMING, T.C.; HUTTENLOCHER, P.R. Recovery cycle of visual cortex of the awake and sleeping cat. Am. J. Physiol., v. 199, n. 2, p. 373-376, 1960. FERNSTROM, J.D. Role of precursor availability in control of monomine biosynthesis in brain. Pharmacol. Rev., v. 63, p. 484-546, 1983. FIEGENSPAN, A.; WÄSSLE, H.; BORMANN, J. Pharmacology of GABA receptor Clchannels in rat retinal bipolar cells. Nature, v. 361, p. 159-162, 1993. FINNIMORE, A.J.; ROEBUCK, M.; SAJKOV, D.; MCEVOY, R.D. The Effects of the GABA agonist, baclofen, on sleep and breathing. European Respiratory Journal, v. 8, p. 230-234, 1995. FOULKES, N.S.; WHITMORE, D.; SASSONE-CORSI, P. Rhythm transcription: the molecular basis of circadian melatonin synthesis. Biol. Cell, v. 89, p. 487-494, 1997. FRANK, M.G.; STRYKER, M.P.; TECOTT, L.H. Sleep and sleep homeostasis in mice lacking the 5-HT2C receptor. Neuropsychopharmacology, v. 27, n. 5, p. 869-873, 2002.. FUCHS, T.; SIEGEL, J.J.; BURGDORF, J.; BINGMAN, V.P. A selective serotonin reuptake inhibitor reduces REM sleep in the homing pigeon. Physiol Behav., v. 87, p.575–581, 2006. GANDOLFO, G.; SCHERSCHLICHT, R.; GOTTESMANN, C. Benzodiazepines promote the intermediate stage at the expense of paradoxical sleep in the rat. Pharmacology Biochemistry and Behavior, v. 49, n. 4, p. 921-927, 1994. GARCÍA, J.J.; REITER, R.J.; GUERRERO, J.M.; ESCAMES, G.; YU, B.P.; OH, C.S.; MUÑOZ-HOYOS, A. Melatonin prevents changes in microsomal membrane fluidity during induced lipid peroxidation. FEBS Lett., v. 408, n. 3, p. 297-300, 1997. GERVASONI, D.; DARRACQ, L.; FORT, P.; SOULIÈRE, F.; CHOUVET, G.; LUPPI, P-H. Electrophysiological evidence that noradrenergic neurons of the rat locus coeruleus are tonically inhibited by GABA during sleep. European Journal of Neuroscience, v. 10, p. 964-970, 1998. GLEESON, S.; WEISSMAN, B.A.; SEGGEL, M.R.; BARRETT, J.E. Neurochemical effects of 5-HT1 receptor ligands in pigeons. European Journal of Pharmacology, v. 229, p. 109-115, 1992. GLENNON, R.A.; METWALLY, K.; DUKAT, M.; ISMAIEL, A.M.; DE LOS ANGELES J.; HERNDON, J.; TEITLER, M.; KHORANA, N. Ketanserin and spiperone as templates for novel serotonin 5-HT (2A) antagonists. Curr. Top.Med. Chem., v. 2, p. 539-558, 2002. GLYKYS, J.; MODY, I. Activation of GABAA receptors: views from outside the synaptic cleft. Neuron., v. 56, p.763–770, 2007. GOTTESMAN, C.; GANDOLFO, G.; ARNAUD, C.; GAUTHIER, P. The Intermediate stage and paradoxical sleep in the rat: influence of three generations of hypnotics. European Journal of Neuroscience, v. 10, p. 409-414, 1998. GOTTESMANN, C. GABA mechanisms and sleep. Neuroscience, v. 111, p.231–239, 2002. GOTTESMANN, C.; GANDOLFO, G.; ZERNICKI. Sleep-Waking cycle in chronic rat preparations with brain stem transected at the caudopontine level. Brain Research Bulletin, v. 36, n. 6, p. 573-580, 1995. GRAEFF, F.G.; VIANA, M.B.; MORA, P.O. Dual role of 5-HT in defense and anxiety. Neuroscience and Biobehavioral Reviews, v. 21, n. 6, p. 791-799, 1997. GRECO, M.; BAENNINGER, R.; GOVERN, J. On the context of yawning: when, where, and why? The Psychological Record., v. 43, p. 175-183, 1993. GURTMAN, C.G.; MORLEY, K.C.; LI, K.M.; HUNT, G.E.; MCGREGOR, I.S. Increased anxiety in rats after 3,4-methylenedioxymethamphetamine: association with serotonin depletion. European Journal of Pharmacology, v. 446, p. 89-96, 2002. HADIDIAN, J. Yawning in an old world monkey Macaca nigra (Primates: Cercopithecidae). Behaviour, v. 75, n. 136, p. 133-147, 1980. HADLEY, Mac E. Endocrine role of the pineal gland. In: ____________. (Ed.). Endocrinology. Upper Saddle River, NJ, USA: Prentice-Hall, Inc., 1996. 518p. HANIG, J.P.; AIELLO, E.; SEIFTER, J. Permeability of the blood-brain barrier to parenteral 5-hydroxytryptamine in the neonate chick. Eur. J. Pharmacol., v. 12, p. 180-182, 1970. HARDELAND, R.; POEGGELER, B. Non-vertebrate Melatonin. J Pineal Res., v. 34, n. 4, p. 233-241, 2003. HASSANAIN, M.; LEVIN, B.E.. Dysregulation of hypothalamic serotonin turnover in dietinduced obese rats. Brain Research., v. 929, p. 175-180, 2002. HAYASHI, A.; SONODA, R.; KIMURA, Y.; TAKASU, T.; SUZUKI, M.; SASAMATA, M.; MIYATA, K. Antiobesity effect of YM348, a novel 5-HT2C receptor agonist, in zucker rats. Brain Research., v. 1011, p. 221-227, 2004. HESS, W.R.. Le sommeil. C.R. Soc. Biol., v.107, p.1333-1364, 1931. HEUSNER, P.A.. Yawning and associated phenomena. Physiol Rev., v. 26, p. 156-168, 1946. HIERDEN, Y.M.V.; KOOLHAAS, J.M.; BOER, S.F.; KORTE, S.M. The control of feather pecking by serotonin. Behavioral Neuroscience., v. 118, n. 3, p. 575-583, 2004. HILL, D.R.; BOWERY, N.G. 3H-baclofen and 3H-GABA bind to bicuculine insensitive GABAB sites in rat brain. Nature, v. 290, p. 149-152, 1981. HO, R.H.; LAVALLEY, A.L. 5-hydroxytryptamine in the spinal cord of the domestic fowl. Brain Research Bulletin, v. 13, p. 427-431, 1984. HOLMES, C.J.; JONES, B.E. Importance of cholinergic, GABAergic, serotonergic and other neurons in the medial medullary reticular formation for sleep-wake states studied by cytotoxic lesions in the cat. Neuroscience, v. 62, n. 4, p 1179-1200, 1994. HOPWOOD, S.E.; STAMFORD, J.A. Multiple 5-HT1 autoreceptor subtypes govern serotonin release in dorsal and median raphé nuclei. Neuropharmacology, v. 40, p. 508-519, 2001. HOUDOUIN, F.; CESPUGLIO, R.; JOUVET, M. Effects induced by the electrical stimulation of the nucleus raphe dorsalis upon hypothalamic release of 5-hydroxyindole compounds and sleep parameters in the rat. Brain Res., v. 565, n. 1, p. 48-56, 1991. HUETHER, G.; POEGGELER, B.; ADLER, L.; RUTHER, E. Effects of indirectely acting 5- HT receptor agonists on circulating melatonin levels in rats. Eur. J. Pharmacol., v. 238, p. 249-254, 1993. HUETHER, G.; POEGGELER, B.; REIMER, A.; GEORGE, A. Effect of tryptophan administration on circulating melatonin levels in chicks and rats: evidence for stimulation of melatonin synthesis and release in the gastrointestinal tract. Life Sci., v. 51, n. 12, p. 945-953, 1992. HUH, S.; KIM, K.H.; HONG, S.S. Effect of β-adrenergic blockers on experimentaly-induced convulsion and narcosis. Yonsei Medical Journal., v. 19, n. 1, p 25-31, 1978. IKEDA, H.; GOTOH, J. Distribution of monoamine-containing cells in the central nervous system of the chicken. Japan. J. Pharmacol., v. 21, p. 763-789, 1971. JACOBS, B.L.; FORNAL, C.A. Activity of serotonergic neurons in behaving animals. Neuropsychopharmacology., v. 21, n. 25, p. 9S-15S, 1999. JANUŠONIS, S.; FITE, K.V.; FOOTE, W. Topographic organization of serotonergic dorsal raphe neurons projecting to the superior colliculus in the Mongolian Gerbil (Meriones unguiculatus). The Journal of Comparative Neurology., v. 413, p. 342-355, 1999. JAYAKUMAR, A.R.; SUJATHA, R.; PAUL, V.; PUVIARASAN, K.; JAYAKUMAR, R. Involvement of nitric oxide and nitric oxide synthase activity in anticonvulsive action. Brain Res Bull., v. 48, p. 387–394, 1999. JONAIDI, H.; BABAPOUR, V.; DENBOW, D.M. GABAergic control of food intake in the meat-type chickens. Physiol Behav., v. 76, p.465–468, 2002. JOHNSTON, G.A.R.; CURTIS, D.R.; BEART, P.M.; GAME, C.J.A.; MCCULLOCH, R.M.; TWITCLIN, B. Cis-and Trans-4-aminocrotonic acid as GABA analogues of restricted conformation. J. Neurochem., v. 24, p. 157-160, 1975. JOUVET, M. Sleep and Serotonin: Na Unfinished Story. Neuropsychopharmacology., v. 21, n. 25, p. 24S-27S, 1999. KARASEK, M.; WINCZYK, K. Melatonin in humans. Journal of Physiology and Pharmacology., v. 57, supp. 5, p. 19-39, 2006. KAUR, S.; SAXENA, R.N.; BIRENDRA, N.; MALLICK, N. GABA in locus coeruleus regulates spontaneous rapid eye movement sleep by acting on GABAA receptors in freely moving rats. Neuroscience Letters., v. 223, p. 105-108, 1997. KAVANAU, J.L. Origin and evolution of sleep: roles of vision and endothermy. Brain Research Bulletin., v. 42, n. 4, p. 245-264, 1997. KHISTI, R.T.; MANDHANE, S.N.; CHOPDE, C.T. The neurosteroid 3a-hydroxy-5apregnan- 20-one induces catalepsy in mice. Neurosci Lett., v. 251, p.85–88, 1998. KRNJEVIC, K.; RANDIC, M.; STRAUGHAN, D.W. Pharmacology of cortical inhibition. J. Physiol. (London), v. 184, p. 78-105, 1966. LAL, S.; GRASSINO, A.; THAVUNDAYIL, J.X.; DUBROVSKY, B. A simple method for the study of yawning in man induced by the dopamine receptor agonist, apomorphine. Prog Neuro Psychopharmacol Biol Psychiat., v. 11, p. 223-228, 1987. LANCEL, M.; FAULHABER, J.; HOLSBOER, F.; RUPPRECHT, R. The GABA(A) receptor antagonist picrotoxin attenuates most sleep changes induced by progesterone. Psychopharmacology (Berl), v. 141, p.213–219, 1999. LANCEL, M.; STEIGER, A. Sleep and its modulation by drugs that affect GABAA receptor function. Angew. Chem. Int. Ed., v. 111, p. 2852-2864, 1999. LANCEL, M. Role of GABAA receptors in the regulation of sleep: initial sleep responses to peripherally administered modulators and agonists. Sleep., v. 22, n. 1, p. 33-42, 1999. LANCEL, M.; CRÖNLEIN, T.A.M.; FAULHABER, J. Role of GABAA receptors in sleep regulation. Differential effects of muscimol and midazolan on sleep in rats. Neuropsychopharmacology., v. 15, n. 1, p. 63-74, 1996. LANGEBARTELS, A.; MATHIAS, S.; LANCEL, M. Acute effects of melatonin on spontaneous and picrotoxin-evoked sleepwake behaviour in the rat. J Sleep Res, v. 10, p.211–217, 2001. LEANDER, P.; VRANG, N.; MOLLER, M. Neuronal projections from the mesencephalic raphe nuclear complex to the suprachiasmatic nucleus and the deep pineal gland of the golden hamster (Mesocricetus auratus). J. Comp. Neurol., v. 399, p. 73-93, 1998. LEHMANN, H.E. Yawning: a homeostatic reflex and its physiological significance. Bull Meninger Clinic., v. 43, p.123–136, 1979. LEIBOWITZ, S.F.; ALEXANDER, J.T. Hypothalamic serotonin in control of eating behavior, meal size and body weight. Biol Psychiatry., v. 44, p. 851-864, 1998. LENZINGER, E.; NEUMEISTER, A.; PRASCHAK-RIEDER, N.;FUCHS, K.;GERHARD, E.;WILLEIT, M.;SIEGHART, W.;KASPER, S.F.;HORNIK, K.;ASCHAUER, H.N. Behavioral efects of typtophan dpletion in sasonal afective disorder associated with the serotoniin transporter gene. Psychiatry Research., v. 85, p. 241-246, 1999. LEVENSON, J.; BYRNE, J.H.; ESKIN, A. Levels of serotonin in the hemolymph of Aplysia are modulated by light?dark cycles and sensitization training. The Journal of Neuroscience., v. 19, n. 18, p. 8094-8103, 1999. LEVINE, E.S.; JACOBS, B.L. Neurochemical afferents controlling the activity of serotonergic neurons in the dorsal raphe nucleus: microiontophoretic studies in the awake cat. The Journal of Neuroscience., v. 12, n. 10, p. 4037-4044, 1992. LIN, J.; SAKAI, K.; VANNI-MERCIER, G.; JOUVET, M. A critical role of the posterior hypothalamus in the mechanisms of wakefulness determined by microinjection of muscumol in freely moving cats. Brain Research., v. 479, p. 225-240, 1989. LIU, R.; JOLA,T.; AGHAJANIAN, G. Serotonin 5-HT2 receptors activate local GABA inhibitory inputs to serotonergic neurons of the dorsal raphe nucleus. Brain Res., v. 873, p.34–45, 2000. LÓPEZ-GIMÉNEZ, J.F.; VILARÓ, M.T.; PALACIOS, J.M.; MENGOD, G. Mapping of 5- HT2A receptors and their mRNA in monkey brain: [3H]MDL100,907 autoradiography and in situ hybridization studies. J. Comp. Neurol., v. 429, p. 571-589, 2001. LYAMIN, O.I.; MUKHAMETOV, L.M.; SIEGEL, J.M. Relationship between sleep and eye state in cetaceans and pinnipeds. Archives Italiennes de Biologie., v. 142, p. 557-568, 2004. MACDONALD, R.L.; TWYMAN, R.E. Kinetic properties and regulation of GABAA receptor channels. Ion Channels, v. 3, p.315–343, 1992. MACLEOD, M.G.; WATSON, A. Thermogenic, thermoregulatory and effects of feneluramine, a 5-hydroxytryptamine agonist, in immature domestic fowl (Gallus domesticus). Comp. Biochem. Physiol. Comp. Physiol., v. 104, n. 2, p. 365-371, 1993. MALLEAU, A.E.; DUNCAN, I.J.H.; WIDOWSKI, T.M.; ATKINSON, J.L. The importance of rest in young domestic fowl. Appl Anim Behav Sci., v.106, p.52–69, 2007. MASCETTI, G.G.; VALLORTIGARA, G. Why do birds sleep with one eye open? Light exposure of the chick embryo as a determinant of monocular sleep. Current Biology., v. 11, p. 971-974, 2001. MATSUMOTO, S.; YAMADA, K., NAGASHIMA, M.; MATSUO, N.; SHIRAKAWA, K.; FURUKAWA, T. Potantiation by serotonergic inhibition of yawning induced by dopamine receptor agonists in rats. Pharmacology Biochemistry & Behavior., v. 32, p. 815-818, 1989. MATSUURA, T.; SANO, Y. Distribution of monoamine-containing nerve fibers in the pineal organ of untreated and sympathectomized dogs. Fluorescence and immunohistochemical studies. Cell Tissue Res., v. 234, p. 519-531, 1983. McINTYRE, I.M.; OXENKRUG, G.F. Efeect of ageing on melatonin synthesis induced by 5- hydroxytryptophan and constant light in rats. Prog. Neuropsychopharmacol. Biol. Psychiatry, v. 15, p. 561-566, 1991. MELIS, M.R.; ARGIOLAS, A.; GESSA, G.L. Evidence that apomorphine induces penile erection and yawning by releasing oxytocin in the central nervous system. European Journal of Pharmacology., v. 164, p. 565-570, 1989. MELIS, M.R.; SALVATORA, S.; ARGIOLAS, A. Dopamine agonists increase nitric oxide production in the paraventricular nucleus of the hypothalamus: correlation with penile erection and yawning. European Journal of Neuroscience., v. 8, p. 2056-2063, 1996. MELTZER, H.Y.; LOWY, M. The serotonin hypothesis of depression. In: ___________. (Eds). Psychopharmacology: The third generation of progress. New York: Raven Press, 1987. p. 513-523. NAMBOODIRI, M.A.; SUGDEN, D.; KLEIN, D.C.; MEFFORD, I.N. 5-Hydroxytryptophan elevates serum melatonin. Science, v. 221, p. 659-661, 1983. NATESAN, A.; GEETHA, L.; ZATZ, M. Rhythm and soul in the avian pineal. Cell Tissue Res., v. 309, p. 35-45, 2002. NATHAN, P.J.; BURROWS, G.; NORMAN, T. R. Evidence for 5-HT1A receptor control of pineal melatonin concentrations in the rat. Eur. Neuropsychopharmacol., v. 8, p. 183-186, 1998. NAUTA, W.J.H. Hypothalamic regulation of sleep in rats. An experimental study. J. Neurophysiol., v. 9, p. 285-316, 1946. NITZ, D.; SIEGEL, J.M. GABA release in posterior hypothalamus across sleep-wake cycle. Am. J. Physiol. , v. 271, n. 40, p. R1707-R1712, 1996. NITZ, D.; SIEGEL, J.M. GABA release in the locus coeruleus as a function of sleep/wake state. Neuroscience., v. 78, n. 3, p. 795-801, 1997a. NITZ, D.; SIEGEL, J.M. GABA release in the dorsal raphe nucleus: role in the control of REM sleep. Am. J. Physiol. v. 273, n. 42, p. R451-R455, 1997b. OSWALD, I. Drugs and sleep. Pharmacological Reviews., v. 20, n. 4, p. 273-303, 1968. PARADES, R.G.; AGMO, A. GABA and behavior: the role of receptor subtypes. Neurosci. Biobehav. Rev., v. 16, p.145-170, 1992. PARENT, A. Comparative anatomy of serotoninergic systems. J. Physiol. (Paris). v. 77, p. 147-156, 1981. PARENT, A.; DESCARRIES, L.; BEAUDET, A. Organization of ascending serotonin systems in the adult rat brain. A radioautographic study after intraventricular administration of [3H]5-hydroxytryptamine. Neuroscience. , v. 6, p. 115-138, 1981. POLO, P.A.; REIS, R.O.; CEDRAZ-MARCEZ, P.L.; CAVALCANTE-LIMA, H.R.; OLIVARES, E.L.; MEDEIROS, M.A.; CÔRTES, W.S.; REIS, L.C. Behavioral and neuropharmacological evidence that serotonin crosses the blood-brain barrier in Coturnix japonica (Galliformes: Aves). Braz J Biol , v. 67, p. 167–171, 2007. PONTES, G.N.; CARDOSO, E.C.; CARNEIRO-SAMPAIO, M.M.S.; MARKUS, R.P. Injury switches melatonin production source from endocrine (Pineal) to paracrine (Phagocytes) – melatonin in human colostrum and colostrum phagocytes. J. Pineal Res., v.41, p. 136-141, 2006. PROTAIS, P.; WINDSOR, M.; MOCAER, E.; COMOY, E. Post-synaptic 5-HT1A receptor involvement in yawning and penile erections induced by apomorphine, physostimine and mCPP. Psychopharmacology (Berl), v. 120, p. 376-383, 1995. RADIL-WEISS, T.; STÝBLOVÁ, V. Influence of thiopental on sleep cycles in rats. Psychopharmacologia , v.11, p.52–64, 1967. RANSON, S.W. Somnolence caused by hypothalamic lesions in the monkey. Archives of Neurology and Psychiatry., v. 41, n. 1, p 1-23, 1939. RATTENBORG, N.C.; MARTINEZ-GONZALEZ, D.; LESKU, J.A. Avian sleep homeostasis: convergent evolution of complex brains, cognition and sleep functions in mammals and birds. Neurosci Biobehav Rev, v. 33, n.3, p. 253-70, 2009. RAYMOND, J. J.; ROBERTSON, D. M.; DINSDALE, H.B. Pharmacological modification of bradykinin induced breakdown of the blood-brain barrier. Can. J. Neurol. Sci, v. 13, p. 214-220, 1986. RECHTSCHAFFEN, A.; BERGMANN, B.M. Sleep deprivation in the rat: an update of the 1989 paper. Sleep, v. 25, p.18–24, 2002. REIS, L.C.; MARINHO, V.R. Influence of 5-HT1A agonist on the feeding behavior of coturnix japonica (Galliformes: Aves). Braz. J. Biol. v. 65, n. 4, p. 675-681, 2005. REIS, L.C.; ALMEIDA, A.C.; CEDRAZ-MERCEZ, P.; OLIVARES, E.L.; MARINHO, JR, A.; THOMAZ, C.M. Evidence indicating participation of the serotonergic system in controlling feeding behavior in Coturnix japonica (Galliformes: Aves). Braz. J. Biol., v. 65, p. 353-361, 2005. REITER, R.J. The ageing pineal gland and its physiological consequences. Bioessays. v. 14, n. 3, p. 169-175, 1992. REITER, R.J. Melatonin, active oxigen species and neurological damage. Drug News Perspect. vol. 11, n. 5, p. 291-296, 1998. REITER, R.J.; KING, T.S.; STEINLECHNER, S.; STEGER, R.W.; RICHARDSON, B.A. Tryptophan administration inhibits nocturnal N-acetyltransferase activity and melatonin content in the rat pineal gland. Evidence that serotonin modulates melatonin production via a receptor-mediated mechanism. Neuroendocrinology, v. 52, p. 291-296, 1990. REITER, R.J.; TAN, D.X.; MANCHESTER, L.C.; PILAR, T.M.; FLORES, L.J.; KOPPISEPI, S.. Medical implications of melatonin: receptor-mediated and receptorindependent actions. Adv Med Sci., v. 52, p. 11-28, 2007. ROSEBROUGH, R.W. Crude protein and supplemental dietary tryptophan effects on growth and tissue neurotransmitter levels in the broiler chicken. British Journal of Nutrition., v. 76, p. 87-96, 1996. SAADOUN, A.; CABRERA, M. C. Effect of the 5-HT1A receptor agonist 8-OH-DPAT on food and water intake in chickens. Physiol. Behav. , v.75, p. 271-275, 2002. SAKO, H.; KOJIMA, T.; OKADO, N. Immunohistochemical study on the development oh serotoninergic neurons in the chick: I. Distribution of cell bodies and fibers. The Journal of Comparative Neurology. , v. 253, p. 61-78, 1986. SALETU, B. Melatonin: a natural hypnotic? Wien klin wochenschr., v. 109, n. 18, p. 714-721, 1997. SANFORD, L.D.; PARRIS, B.; TANG, X. GABAergic regulation of the central nucleus of the amygdale: implications for sleep control. Brain Res, v. 956, p. 276–284, 2002. SCHINO, G.; AURELI, F. Do men yawn more than women? Ethology and Sociobiology. , v. 10, p. 375-378, 1989. SCHMITT, A.; MÖSSNER, R.; GOSSMANN, A.; FISCHER, I.G.; GORBOULEV, V.; MURPHY, D.L.; KOEPSELL, H.; LESCH, K.P. Organic cation transporter capable of transporting serotonin is up-regulated in serotonin transporter-deficient mice. J. Neurosci. Res., v. 71, p. 701-709, 2003. SHARP, P.J.; FOLLETT, B.K. The distribution of monoamines in the hypothalamus of the Japanese quail, Coturnix coturnix japonica,. Zeitschryft für Zellforschung., v. 90, p. 245-262, 1968. SIEGHART, W. Structure and pharmacology of γ-aminobutyric AcidA receptor subtypes. Pharmacological Reviews. v. 47, n. 2, p. 181-234, 1995. SMITH, C.T.; MISKIMAN, D.E. Increases in paradoxical sleep as a result of amygdaloid stimulation. Physiology and Behaior. v. 15, p. 17-19, 1975. STANCAMPIANO, R.; MELIS, M.R.; ARGIOLAS, A. Penile erection and yawning induced by 5-HT1C receptor agonists in male rats: relationship with dopaminergic and oxytocinergic transmission. Eur. J. Pharmacol., v. 261, p. 149-155, 1994. STEARDO, L.; MONTELEONE, P.; CANNIZZARO, C.; MAJ, M.; CUOMO, V. Serotonergic modulation of the rat pineal gland activity: In vivo evidence for a 5-hydroxytryptamine (2C) receptor involvement. J. Pharmacol. Exp Ther., v. 295, p. 266-273, 2000. STEFFENS, S.M.; CASAS, D.C.; MILANEZ, B.C.; FREITAS, C.G.; PASCHOALINI, M.A.; MARINO-NETO, J. Hypophagic and dipsogenic effects of central 5-HT injections in pigeons. Brain Research Bulletin., v. 44, n. 6, p. 681-688, 1997. STOKKAN, K.A.; REITER, R.J.; NONAKA, K.O.; LERCHL, A.; YU, B.P.; VAUGHAN, M.K. Food restriction retards aging of the pineal gland. Brain Res., v. 545, p. 66-72, 1991. SUGDEN, D.; NAMBOODIRI, M.A.; KLEIN, D.C.; GRADY JR., R.K.; MEFFORD, I.N. Ovine pineal indoles: effects of l-tryptophan or l-5-hydroxytryptophan administration. J. Neurochem., v. 44, p. 769-772, 1985. TAHERI, S.; MIGNOT, E. The genetics of sleep disorders. Lancet Neurol. , v.1, p. 242–250, 2002. TAKAGI, T.; ANDO, R.; OHGUSHI, A.; YAMASHITA, T.; DOBASHI, E.; HUSSAINUSUF, H.; ONODERA, R.; BUNGO, T.; SATO, H.; FURUSE, M. Intracerebroventricular injection of pipecolic acid inhibits food intake and induces sleeping-like behaviors in the neonatal chick. Neurosci Lett, v. 310, p. 97–100, 2001. TAKAGI, T.; BUNGO, T.; TACHIBANA, T.; SAITO, E.S; SAITO, S.; YAMASAKI I.; TOMONAGA, S.; DENBOW, D.M.; FURUSE, M. Intracerebroventricular administration of GABA-A and GABA-B receptor antagonists attenuate feeding and sleeping-like behavior induced by L-pipecolic acid in neonatal chicks. J Neurosci Res, v. 73:270–275, 2003. TOHYAMA, Y.; YAMANE, F.; MERID, M.F.; DIKSIC, M. Effects of selective 5-HT1A receptor antagonists on regional serotonin synthesis in the rat brain: an autoradiographic study with α-[14C] methyl- L- tryptophan. European Neuropsychopharmacology., v. 11, p. 193-202, 2001. TRULSON, M.E.; JACOBS, B. L.; MORRISON, A. R. Raphe unit activity during REM sleep in normal cats and in pontine lesioned cats displaying REM sleep without atonia. Brain Research., v. 226, p. 75-91, 1981. TRULSON, M.E.; BRANDSTETTER, J.W.; CRISP, T.; JACOBS, B.L. Behavioral effects of quipazine in the cat. Eur. J. Pharmacol., v. 78, p. 295-305, 1982. TYCE, G.M. Origin and metabolism of serotonin. J.Cardiovasc. Pharmacol., v. 16, p. S1-S7, 1990. UNDERWOOD, H.; SIOPES, T. Circadian organization in Japanese quail. J. Exp. Zool. v. 323, n. 3, p. 557-566. VALVERDE, A.; BIENZLE, D.; SMITH, D.A.; DYSON, D.H.; VALLIANT, A. E. Intraosseous cannulation and drug administration for induction of anesthesia in chickens. Vet Surg , v.22, p.240–244, 1993. VALENCIA-FLORES, M.; CAMPOS-SEPULVEDA, E.; GALINDO-MORALES, J.A.; LUJAN, M.; COLOTLA, V.A. Behavioral and biochemical correlates of chronic administration of quipazine. PharmachologyBiochemistry & Behavior. v. 36, p. 299-304, 1990. VAN LUIJTELAAR, E.L.J.M; VAN DER GRINTEN, C.P.M.; BLOKHUIS; H.J.; COENEN, A.M.L. Sleep in the domestic hen (Gallus domesticus). Physiol Behav, v. 41:p. 409–414, 1987. VANNI-MERCIER, G.; SAKAI, K.; LIN, J.S.; JOUVET, M. Carbachol microinjections in the mediodorsal pontine tegmentum are unable to induce paradoxical sleep after caudal pontine and prebulbar transections in the cat. Neuroscience Letters., v. 130, p. 41-45, 1991. WAMBEBE, C. Influence of some GABAergic agents on nitrazepam-induced sleep in the domestic fowl (Gallus domesticus). Jpn J Pharmacol , v. 33p. 1111–1118, 1983. WANG, R.Y.; AGHAJANIAN, G.K. Inhibition of neurons in the amygdala by dorsal raphe stimulation: mediation through a direct serotonergic pathway. Brain Res., v. 120, p. 85-102, 1977. WINKLER, T.; SHARMA, H.S.; STALBERG, E.; OLSSON, Y.; DEY, P.K. Impairment of blood-brain barrier function by serotonin induces desynchronization of spontaneous cerebral cortical activity: Experimental observations in the anaesthetized rat. Neuroscience, v. 68, p. 1097-1104, 1995. WU, X.; KEKUDA, R.; HUANG, W.; FEI, YJ.; LEIBACH, FH.; CHEN, J.; CONWAY, S.J.; GANAPATHY, V. Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake 2) and evidence for the expression of the transporter in the brain. J. Biol. Chem., v. 273, p. 32776-32786, 1998. YAMAMOTO, I. Studies on the structure-activity relationship of allyl substituted oxopyrimidines searching for the novel antagonist or agonist of barbiturates to the sleep mechanism based on the uridine receptor theory-barbituric acid to uridine (part I). Yakugaku Zasshi , v. 125, p. 73–120, 2005. ZDANOVA, I.V. Melatonin as a hypnotic: Pro. Sleep Medicine Reviews. V. 9, p. 51-65, 2005. ZDANOVA, I.V.; WURTMAN, R.J. Efficacy of melatonin as a sleep-promoting agent. Journal of Biological Rhythms., v. 12, n. 6, p. 644-650, 1997.por
dc.rightsAcesso Abertopor
dc.subjectSonopor
dc.subjectcodornaspor
dc.subjectcomportamentopor
dc.subjectSleepeng
dc.subjectquailseng
dc.subjectbehavioreng
dc.subject.cnpqFisiologiapor
dc.titleEstudo neurobiológico de componentes do sono em codornas (Coturnix japonica) (Temminck Schlegel, 1849) (Aves: Galliformes)por
dc.title.alternativeStudy of neurobiologic components of the sleep in quails (Coturnix japonica) (Temminck Schlegel, 1849) (Birds: Galliformes)eng
dc.typeTesepor
Appears in Collections:Doutorado em Biologia Animal

Files in This Item:
File Description SizeFormat 
2009 - Patricia de Almeida Polo.pdf1.01 MBAdobe PDFThumbnail

Download/Open Preview
Show simple item record Recommend this item


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.