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dc.creatorFazio Junior, Pedro Ivan-
dc.creator.Latteshttp://lattes.cnpq.br/2399464111506427por
dc.contributor.advisor1Coumendouros, Katherina-
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/6886641792170591por
dc.contributor.referee1Fernandes, Julio Israel-
dc.contributor.referee2Souza, Clarissa Pimentel de-
dc.contributor.referee3Azevedo, Thaís Ribeiro Correia-
dc.date.accessioned2019-09-19T14:08:15Z-
dc.date.issued2012-02-23-
dc.identifier.citationFAZIO JUNIOR, Pedro Ivan. Avaliação clínica e eficácia de uma coleira contendo flumetrina e propoxur no controle de Ctenocephalides felis felis e Rhipicephalus sanguineus em cães. 2012. 48 f. Dissertação (Programa de Pós-Graduação em Ciências Veterinárias) - Universidade Federal Rural do Rio de Janeiro, Seropédica.por
dc.identifier.urihttps://tede.ufrrj.br/jspui/handle/jspui/2903-
dc.description.resumoO objetivo deste trabalho foi avaliar a eficácia de uma coleira impregnada com Flumetrina (2,5%) e Propoxur (10%) sobre adultos de Ctenocephalides felis felis e Rhipicephalus sanguineus em cães Beagle com avaliação de possíveis alterações da colinesterase sérica (butirilcolinesterase) após o uso da coleira. Para isso foram utilizados 20 cães da raça Beagle, divididos em dois grupos, onde em 10 animais foram colocadas as coleiras impregnadas e os outros 10 sem nenhum tratamento (controle). Cada cão foi infestado com 50 casais de C. felis felis e 25 casais de R. sanguineus semanalmente no primeiro mês e a partir do segundo mês quinzenalmente até o dia +210. Quarenta e oito horas após as infestações foram realizadas avaliações com contagem de pulgas e carrapatos vivos recuperados nos animais. Para dosagem da colinesterase sérica foram coletadas amostras de sangue dos animais nos dias -14, -7, +1, +5, +10, +30, +45, +60, +75, +90, +105, +120, +135, +150, +165, +180, +195 e +210. Todos os animais foram avaliados semanalmente em relação a sinais clínicos compatíveis com intoxicação. Posteriormente ao término do experimento de eficácia as coleiras foram removidas e após sete dias foi realizada nova dosagem da colinesterase. A eficácia para C. felis felis foi superior a 80% até o dia +168 após tratamento. A eficácia para R. sanguineus foi superior a 80% até o dia +182. Foi verificado que a coleira não diminuiu significativamente (p≤0,05) os níveis séricos de butirilcolinesterase nos cães comparando-se as médias antes e após o tratamento, no entanto, a atividade sérica da colinesterase aumentou significativamente (p≤0,05) após a retirada da coleira. Evidenciou-se que a coleira a base de propoxur e flumetrina apresenta eficácia superior a cinco meses sobre C. felis felis e R. sanguineus. A alteração da colinesterase sérica dos animais pelo propoxur não foi relevante e nenhum sinal de toxicidade foi observado durante o período experimentalpor
dc.description.abstractThe objective of this study was to evaluate the efficacy of a collar impregnated with flumethrin (2.5%) and propoxur (10%) against adults of Ctenocephalides felis felis and Rhipicephalus sanguineus on Beagle dogs, and to evaluate possible changes in serum cholinesterase (butyrylcholinesterase) after the use of the collar. Twenty Beagle dogs were divided into two groups, on 10 animals impregnated collars were placed and the other 10 remained untreated (control group). Each dog was infested with 50 pairs of C. felis felis and 25 pairs of R. sanguineus weekly during the first month, and after the second month every two weeks until day +210. Forty-eight hours after infestation, live fleas and ticks were recovered and counted from the animals. For determination of serum cholinesterase, blood samples were collected on days -14, -7, +1, +5, +10, +30, +45, +60, +75, +90, +105, +120, +135, +150, +165, +180, +195 and +210. All animals were evaluated weekly for signs consistent with clinical intoxication. At the end of the trial, the collars were removed, and after seven days, new measurement of cholinesterase was done. . The efficacy for C. felis felis was over 80% for up to day +168 after treatment. The efficacy for R. sanguineus was over 80% up to day +182. It was found that the collar has not decreased significantly (p ≤ 0.05) serum butyrylcholinesterase in dogs by comparing the means before and after treatment, however, the serum cholinesterase activity was significantly increased (p ≤ 0.05) after removal of the collars. It was evident that the impregnated with propoxur and flumethrin has an efficacy superior to five months in the control of C. felis felis and R. sanguineus. The alteration in serum cholinesterase levels by propoxur was not relevant and no signs of toxicity were observed during the experimental periodeng
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dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico - CNPQpor
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dc.languageporpor
dc.publisherUniversidade Federal Rural do Rio de Janeiropor
dc.publisher.departmentInstituto de Veterináriapor
dc.publisher.countryBrasilpor
dc.publisher.initialsUFRRJpor
dc.publisher.programPrograma de Pós-Graduação em Ciências Veterináriaspor
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W.; WHITACRE, D. M. An Introduction to Insecticides (4th edition), 2009. Disponível em: <http://ipmworld.umn.edu/chapters/ware.htm>. Acesso em: 09 dez. 2011. WINGFIELD, W. E. Segredos em Medicina Veterinária. Porto Alegre: Artmed, 1998. 546 p. WITCHEY-LAKSHMANAN, L. C. Long-acting control of ectoparasites: a review of collar technologies for companion animals. Advanced Drug Delivery Reviews, v. 38, n. 2, p. 113- 122, 1999.por
dc.rightsAcesso Abertopor
dc.subjectPulgaspor
dc.subjectCarrapatospor
dc.subjectButirilcolinesterasepor
dc.subjectFleaseng
dc.subjectTickseng
dc.subjectButyrylcholinesteraseeng
dc.subject.cnpqMedicina Veterináriapor
dc.titleAvaliação clínica e eficácia de uma coleira contendo flumetrina e propoxur no controle de Ctenocephalides felis felis e Rhipicephalus sanguineus em cãespor
dc.title.alternativeClinical evaluation and efficacy of a collar containing flumethrin and propoxur in the control of Ctenocephalides felis felis and Rhipicephalus sanguineus in dogseng
dc.typeDissertaçãopor
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